What Is HbA1c (Hemoglobin A1c)?
HbA1c measures the percentage of haemoglobin in red blood cells that has glucose attached to it; because red blood cells live approximately 2–3 months, HbA1c reflects average blood sugar control over the preceding 2–3 months and is used to diagnose and monitor diabetes.
Your red blood cells carry a protein called haemoglobin, whose job is to transport oxygen around your body. When glucose — blood sugar — circulates in your bloodstream, some of it sticks to that haemoglobin, forming what scientists call glycated haemoglobin, or HbA1c. Because red blood cells live for approximately two to three months before your body replaces them, the percentage of haemoglobin that has glucose attached reflects your average blood sugar levels across that entire window. A single fasting glucose test only captures a moment in time; HbA1c captures the whole season. Doctors order this test to screen for prediabetes and diabetes, to confirm a diabetes diagnosis, and — for people already living with diabetes — to check whether blood sugar management is on track over time. Here is what the numbers mean, according to the American Diabetes Association. A result below 5.7% falls in the normal range, meaning your average blood sugar has been within a healthy zone. A result between 5.7% and 6.4% indicates prediabetes — your blood sugar is running higher than ideal, but has not yet crossed the diagnostic threshold for diabetes. A result of 6.5% or above, confirmed on a repeat test, meets the diagnostic criterion for diabetes. For people who already have a diabetes diagnosis and are actively managing it, a typical treatment target is keeping HbA1c at or below 7%, though your own target may differ based on your age, health history, and other factors your doctor weighs. Numbers outside any of these ranges do not automatically tell the full story. Certain medical conditions — such as anaemia or kidney disease — can shift HbA1c readings in ways that don't accurately reflect your true blood sugar. Your healthcare provider is best placed to interpret your specific result in context.
Definition source: American Diabetes Association. Standards of Care in Diabetes. https://diabetesjournals.org/care/article/46/Supplement_1/S1/148054
Normal Reference Ranges for HbA1c (Hemoglobin A1c)
| Population | Reference Range | Unit |
|---|---|---|
| Normal (no diabetes) | — – 5.6 | % |
| Prediabetes | 5.7 – 6.4 | % |
| Diabetes — diagnostic threshold | 6.5 – — | % |
| Typical treatment target in people with established diabetes | — – 7 | % |
Source: American Diabetes Association. Standards of Care in Diabetes. 2024.
Reference ranges vary slightly between laboratories. Always compare your result against the ranges printed on your specific lab report, and discuss interpretation with your healthcare provider.
What Causes Abnormal HbA1c (Hemoglobin A1c) Levels?
Common Causes of High HbA1c (Hemoglobin A1c)
- Type 2 diabetes (most common)
- Type 1 diabetes
- Prediabetes with inadequate lifestyle or medication management
- Iron deficiency anemia (can falsely elevate HbA1c)
- Chronic kidney disease (red cell lifespan is altered)
Source: NHS. Type 2 diabetes. https://www.nhs.uk/conditions/type-2-diabetes/
Common Causes of Low HbA1c (Hemoglobin A1c)
- Haemolytic anemia or other conditions shortening red cell lifespan (red cells are replaced faster, lowering HbA1c artificially)
- Recent blood transfusion (new donated red cells have no glucose attached)
- Sickle cell disease and other haemoglobinopathies (can give falsely low or unreliable readings)
- Iron supplementation (increases red cell turnover)
- Hypoglycaemia-prone states
Source: MedlinePlus. Hemoglobin A1c Test. https://medlineplus.gov/lab-tests/hemoglobin-a1c-hba1c-test/
Symptoms Associated with HbA1c (Hemoglobin A1c) Imbalance
Symptoms of High HbA1c (Hemoglobin A1c)
- Increased thirst and frequent urination
- Fatigue
- Blurred vision
- Slow-healing wounds
- Frequent infections
- Numbness or tingling in the feet or hands
- Often no symptoms in early or mild elevation
Symptoms of Low HbA1c (Hemoglobin A1c)
- Abnormally low HbA1c typically does not cause direct symptoms
- Symptoms of the underlying cause (e.g., anaemia: fatigue, pallor, shortness of breath)
Source: NHS. Type 2 diabetes — symptoms. https://www.nhs.uk/conditions/type-2-diabetes/symptoms/
Frequently Asked Questions About HbA1c (Hemoglobin A1c)
What does an HbA1c test actually measure?
Your HbA1c test measures the percentage of haemoglobin — a protein inside your red blood cells — that has glucose (sugar) attached to it. Because red blood cells live for approximately two to three months, this percentage acts like an average diary of your blood sugar levels over that whole period, rather than a single-day reading. Doctors use it to diagnose prediabetes and diabetes and to track how well blood sugar management is working over time. Talk with your healthcare provider about what your specific result means for your health.
What is a normal HbA1c range?
According to the American Diabetes Association, an HbA1c below 5.7% is considered normal, meaning blood sugar has been in a healthy range on average. A reading between 5.7% and 6.4% signals prediabetes — higher than ideal, but not yet at a diabetes diagnosis. A result of 6.5% or above meets the diagnostic threshold for diabetes. For people already managing diabetes, a common treatment target is 7% or below, though individual targets vary. Reference ranges can also be affected by certain medical conditions, so always discuss your specific number with your healthcare provider.
What causes a high HbA1c result?
The most common reasons for an elevated HbA1c are type 2 diabetes and type 1 diabetes, where the body either doesn't produce enough insulin or can't use it properly, leaving excess glucose circulating in the blood and sticking to haemoglobin. Prediabetes with inadequate lifestyle or medication management can also push the number up. In some cases the elevation isn't a true reflection of blood sugar at all — iron deficiency anaemia and chronic kidney disease can both alter red blood cell behaviour in ways that falsely raise HbA1c readings. Your healthcare provider can help you understand the likely cause behind your specific result.
What causes a low HbA1c result?
A lower-than-expected HbA1c isn't always good news — it can sometimes be misleading rather than a sign of excellent blood sugar control. Conditions that shorten red blood cell lifespan, such as haemolytic anaemia, cause cells to be replaced faster, so less glucose has time to attach — producing an artificially low reading. A recent blood transfusion introduces donated red cells with no glucose attached, also pulling the number down. Sickle cell disease and other haemoglobin variants can make HbA1c unreliable in either direction. Iron supplementation and hypoglycaemia-prone states are additional factors. Discuss any low reading with your healthcare provider to understand what it means for you.
What symptoms are linked to a high HbA1c?
Persistently elevated blood sugar — reflected in a high HbA1c — can produce a recognisable set of symptoms: increased thirst, frequent urination, unexplained fatigue, blurred vision, slow-healing wounds, frequent infections, and numbness or tingling in the feet or hands. That said, many people with mildly or moderately high HbA1c experience no symptoms at all, which is one reason regular testing matters. Symptoms alone can't tell you your HbA1c level, and a high reading can have more than one cause. If you're experiencing any of these signs alongside an elevated result, speak with your healthcare provider as soon as possible.
How often should I get my HbA1c tested?
How frequently you need an HbA1c test depends on your individual situation — your current result, whether you have a diabetes or prediabetes diagnosis, any recent changes to your medication or lifestyle, and other health factors your doctor tracks. Because the test reflects a two-to-three month average, retesting sooner than that window typically won't capture meaningful change. Some people are tested twice a year; others more or less frequently depending on how stable their blood sugar management is. There is no universal schedule that fits everyone. Your healthcare provider is the right person to set a testing cadence that makes sense for your specific circumstances.
Track Your HbA1c (Hemoglobin A1c) Over Time
A single lab result is a snapshot. Serumo lets you log every result, visualize trends, and understand what changes in your hba1c (hemoglobin a1c) level mean for your health over months and years.
Sources & References
- [1] Hemoglobin A1c (HbA1c) Test. MedlinePlus, National Library of Medicine, 2023. https://medlineplus.gov/lab-tests/hemoglobin-a1c-hba1c-test/
- [2] Standards of Care in Diabetes. American Diabetes Association, 2024. https://diabetesjournals.org/care/article/46/Supplement_1/S1/148054
- [3] Type 2 diabetes. NHS (National Health Service, UK), 2023. https://www.nhs.uk/conditions/type-2-diabetes/