What Is Ferritin?
Ferritin is a protein that stores iron inside cells; measuring it in the blood reflects the body's total iron stores and is the most sensitive single test for diagnosing iron deficiency.
Ferritin is a protein that stores iron inside your cells. Measuring it in your blood reflects your body's total iron stores, and it is the most sensitive single test for diagnosing iron deficiency. In simple terms, your ferritin level tells you and your doctor how much iron you have tucked away for future use, much like checking the balance in a savings account rather than the cash in your pocket. Doctors order this test for several reasons. If you feel constantly tired, look pale, or have symptoms that suggest your iron might be running low, a ferritin test can confirm whether your stores are depleted. On the other hand, your doctor may want to check whether you have too much iron building up, which can happen with certain inherited or chronic conditions. Understanding what your number means depends partly on who you are, because healthy ranges differ by age and sex. For adult men aged 18 and older, a typical range runs from 12 to 300 ng/mL. For premenopausal adult women, the range is 12 to 150 ng/mL, while postmenopausal women fall between 12 and 263 ng/mL. Children also have their own ranges: those aged 1 to 5 years typically measure 6 to 24 ng/mL, and children aged 6 to 9 years fall between 10 and 55 ng/mL. A result below your expected range often points toward low iron stores, while a result above it can reflect iron overload or inflammation in the body. Because ferritin can shift for many reasons, your number is just one piece of a larger picture. Your healthcare provider can interpret it alongside your symptoms and other tests to understand what is really happening for you.
Definition source: MedlinePlus, National Library of Medicine. https://medlineplus.gov/lab-tests/ferritin-blood-test/
Normal Reference Ranges for Ferritin
| Population | Reference Range | Unit |
|---|---|---|
| Adult males (≥18 years) | 12 – 300 | ng/mL |
| Adult females (≥18 years, premenopausal) | 12 – 150 | ng/mL |
| Adult females (≥18 years, postmenopausal) | 12 – 263 | ng/mL |
| Children 1–5 years | 6 – 24 | ng/mL |
| Children 6–9 years | 10 – 55 | ng/mL |
Source: Mayo Clinic Laboratories
Reference ranges vary slightly between laboratories. Always compare your result against the ranges printed on your specific lab report, and discuss interpretation with your healthcare provider.
What Causes Abnormal Ferritin Levels?
Common Causes of High Ferritin
- Hereditary hemochromatosis (genetic iron overload disorder)
- Liver disease, including hepatitis, cirrhosis, and nonalcoholic fatty liver disease (NAFLD)
- Inflammatory conditions such as rheumatoid arthritis, lupus, and other autoimmune diseases
- Infection or sepsis (ferritin is an acute-phase reactant that rises with inflammation)
- Metabolic syndrome and obesity
- Alcohol use disorder
- Hyperthyroidism
- Certain cancers, including lymphoma and leukemia
- Frequent blood transfusions
- Adult-onset Still's disease
Source: NHS. Haemochromatosis. https://www.nhs.uk/conditions/haemochromatosis/; MedlinePlus. Ferritin Blood Test. https://medlineplus.gov/lab-tests/ferritin-blood-test/
Common Causes of Low Ferritin
- Iron deficiency (most common cause of low ferritin worldwide)
- Iron deficiency anemia
- Malabsorption disorders such as celiac disease and Crohn's disease
- Inadequate dietary iron intake (common in vegetarian and vegan diets without supplementation)
- Pregnancy (increased iron demand)
- Heavy or prolonged menstrual bleeding
- Chronic gastrointestinal blood loss (e.g., ulcers, polyps)
- Hookworm infestation (common cause globally)
Source: World Health Organization. Iron Deficiency Anaemia: Assessment, Prevention, and Control. 2001. https://www.who.int/publications/i/item/9241547014
Symptoms Associated with Ferritin Imbalance
Symptoms of High Ferritin
- Often asymptomatic in early stages
- Joint pain, particularly in the knuckles
- Fatigue and weakness
- Abdominal pain
- Darkening or bronzing of the skin (in advanced hemochromatosis)
- Reduced sex drive
- Irregular heartbeat (in severe cases)
Symptoms of Low Ferritin
- Fatigue and persistent tiredness
- Shortness of breath with minimal exertion
- Pale skin, pale gums, or pale inner eyelids
- Brittle nails and hair loss or thinning
- Restless leg syndrome
- Brain fog and difficulty concentrating
- Cold hands and feet
- Frequent headaches
- Sore or swollen tongue (glossitis)
- Pica (craving non-food items such as ice, dirt, or clay)
Source: National Heart, Lung, and Blood Institute. Iron-Deficiency Anemia. https://www.nhlbi.nih.gov/health/anemia/iron-deficiency-anemia
Frequently Asked Questions About Ferritin
What is a ferritin blood test and what does it measure?
A ferritin blood test measures the amount of ferritin, a protein that stores iron inside your cells, circulating in your blood. Because the level of ferritin in your blood reflects your body's total iron stores, this test gives doctors a reliable window into how much iron you have in reserve. It is actually the most sensitive single test for diagnosing iron deficiency, which means it can reveal a shortage of iron before other signs appear. The test usually involves a simple blood draw. Your result, measured in ng/mL, becomes most meaningful when reviewed alongside your overall health, so discuss what your specific ferritin reading means with your healthcare provider.
What is a normal ferritin range?
Normal ferritin ranges depend on your age and sex. For adult men aged 18 and older, a typical range is 12 to 300 ng/mL. Premenopausal adult women generally fall between 12 and 150 ng/mL, while postmenopausal women range from 12 to 263 ng/mL. Children have lower ranges: those aged 1 to 5 years typically measure 6 to 24 ng/mL, and children aged 6 to 9 years fall between 10 and 55 ng/mL. Different laboratories may report results slightly differently, and your personal health history matters when interpreting any number. To understand where your own result fits and what it means for you, talk it through with your healthcare provider.
What does high ferritin mean?
A high ferritin level can mean your body is storing too much iron, or it can signal inflammation, since ferritin rises in response to it. One cause is hereditary hemochromatosis, a genetic disorder that leads to iron overload. Other causes include liver disease such as hepatitis, cirrhosis, and nonalcoholic fatty liver disease, along with inflammatory conditions like rheumatoid arthritis and lupus. Infection or sepsis can raise it too, as can metabolic syndrome and obesity, alcohol use disorder, hyperthyroidism, certain cancers including lymphoma and leukemia, frequent blood transfusions, and adult-onset Still's disease. Because so many conditions can lift your ferritin, a single high reading rarely tells the whole story. Review your result with your healthcare provider to understand the cause.
What causes low ferritin?
Low ferritin usually points to depleted iron stores. The most common cause worldwide is iron deficiency, which can progress to iron deficiency anemia. Several situations can drain your iron: malabsorption disorders such as celiac disease and Crohn's disease, inadequate dietary iron, which is common in vegetarian and vegan diets without supplementation, and the increased iron demands of pregnancy. Heavy or prolonged menstrual bleeding and chronic gastrointestinal blood loss from ulcers or polyps can also lower your stores over time. In many parts of the world, hookworm infestation is a frequent cause. Pinpointing why your ferritin is low matters as much as the number itself, so discuss your specific result and possible causes with your healthcare provider.
What are the symptoms of low ferritin or iron deficiency?
When your ferritin runs low, you may notice fatigue and persistent tiredness, along with shortness of breath even after mild activity. Your skin, gums, or the inside of your eyelids may look pale. Some people develop brittle nails, hair loss or thinning, restless leg syndrome, or brain fog that makes it hard to concentrate. Cold hands and feet, frequent headaches, and a sore or swollen tongue can also appear. A more unusual sign is pica, a craving for non-food items such as ice, dirt, or clay. These symptoms can overlap with many other conditions, so if you recognize several of them, talk with your healthcare provider about whether testing is right for you.
Can my ferritin level change over time, and should I retest?
Yes, your ferritin level can shift over time, sometimes considerably. Because ferritin rises with inflammation and falls as iron stores are used up, your number can move in response to illness, diet, blood loss, pregnancy, or changes in an underlying condition. A single reading captures only one moment, which is why your doctor may suggest repeating the test to see how your level trends. Comparing results over weeks or months often reveals more than any one value alone. Tracking your ferritin alongside how you feel can help you and your care team spot meaningful patterns. Decisions about when and whether to retest depend on your situation, so discuss the right timing and approach with your healthcare provider.
Track Your Ferritin Over Time
A single lab result is a snapshot. Serumo lets you log every result, visualize trends, and understand what changes in your ferritin level mean for your health over months and years.
Sources & References
- [1] Ferritin Blood Test. MedlinePlus, National Library of Medicine, 2023. https://medlineplus.gov/lab-tests/ferritin-blood-test/
- [2] Ferritin — Test Catalog. Mayo Clinic Laboratories, 2024. https://www.mayocliniclabs.com/test-catalog/overview/8188
- [3] Iron-Deficiency Anemia. National Heart, Lung, and Blood Institute (NHLBI), 2023. https://www.nhlbi.nih.gov/health/anemia/iron-deficiency-anemia
- [4] Iron Deficiency Anaemia: Assessment, Prevention, and Control. World Health Organization (WHO), 2001. https://www.who.int/publications/i/item/9241547014
- [5] Haemochromatosis. NHS (National Health Service, UK), 2023. https://www.nhs.uk/conditions/haemochromatosis/